Airless packaging with alcohol

BelassiBelassi Member, PCF student
I have for a long time wanted to be able to use a lot more than 0.2% of glycrrhizic acid in a skin cream. The problem is, 0.2% is the limit solubility in pretty much anything except ethyl alcohol. It's quite soluble in say, 25% ethanol.
Unfortunately all my attempts to use it resulted in unpleasant crystal precipitation because the alcohol evaporates out of it and escapes.
Now that I have airless pumps in stock, I am wondering, it it is maybe worth trying this concept again? Will the pump resist say, 5% alcohol OK?
Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.

Comments

  • Can't answer the packaging question but isopentyldiol is also an effective solvent for your active.

    http://www.thesoapkitchen.co.uk/acatalog/PDF_IPD_MMB_in_SOFW_0_.2015.pdf
  • johnbjohnb Member, Professional Chemist
    The potassium, sodium and ammonium salts are soluble in water.
  • BelassiBelassi Member, PCF student
    Elise thanks for that. Heaven knows how I'm going to obtain that in Mexico...
    Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.
  • BelassiBelassi Member, PCF student
    Johnb: Do you think I will be able to convert the pure acid to the potassium salt? Would it be as simple as reacting it with potassium hydroxide using 1 mol to 1 mol?
    Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.
  • Bill_TogeBill_Toge Member, Professional Chemist
    in my experience, airless packaging is very robust; as long as the closure fits properly and consistently, you shouldn't have a problem with an alcohol-containing product
    UK based formulation chemist. Strongest subjects: hair styling, hair bleaches, hair dyes (oxidative and non-oxidative) I know some stuff about: EU regulations, emulsions (O/W and W/O), toothpaste, mouthwash, shampoos, other toiletries
  • BelassiBelassi Member, PCF student
    I'm going to see if I can obtain isopentyldiol in Mexico because it's a good stabiliser for the vit C compound. Thanks for your answer Bill. Having had some success with converting the pure acid to the dipotassium salt I think I will use that instead which means I don't need alcohol.
    Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.
  • BelassiBelassi Member, PCF student
    Can't find this in Mexico and for that matter, I can't find a US supplier either.
    Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.
  • So far I've been buying smaller quantities through this UK reseller. Shipping costs are reasonable.

    http://www.thesoapkitchen.co.uk/cgi-bin/sh000002.pl?WD=isopentyldiol&PN=Isopentyldiol.html#SID=55 

    They have pack sizes of up to 10 kg. Unsure if shipping expense gets prohibitive when purchasing in bulk.
  • BelassiBelassi Member, PCF student
    At 1Kg the shipping cost is twice the price of the product. I think I will use my alternative solution to this problem, which is to synthesise the dipotassium salt which is soluble, rather than dissolve the pure acid in DPG. Thanks for your response.
    Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.
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