epidermal growth factor

Currently, I found some of these ingredients in cosmetic products from korea.
EGF, IGF, FGF. One of that mention it contains 10% of EGF, IGF, FGF. 
rh-Oligopeptide-1
SH-polypeptide-11
Sh-Oligopeptide - 2
Is there any regulation or any country prohibited of using this kind of material?
I check online, it says china had banned the use of EGF in cosmetic, but allows the use of Oligopeptide-1, what is the difference?

Thanks.

Comments

  • There's a difference between fermented-derived/synthetic peptides that are supposed to "be identical to" or "stimulate" EGF, and human epidermal growth factor (rhEGF), the latter which is supposed to be sourced from human cells and produced from recombinant DNA technology.
    The peptides you listed are fairly large, so they'd have difficulty in penetrating the skin. I don't think they'd penetrate the skin at all, especially in the typical cosmetic emulsion. Those peptides would be allowable in cosmetics if the manufacturer proved they were safe and not drugs, AKA not penetrating the skin at all.
  • twokchu said:
    Is there any regulation or any country prohibited of using this kind of material?
    Yes, here is some information from Australia.

    Where it is only allow when: "in topical cosmetic preparations containing 0.0002% or less of transgenic, plant-made epidermal growth factor".
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